Renaissance contributions enriched their artistic heritage, such as the remarkable altar of tiles made in 1504 by Francisco Niculoss Pisano or the pictorial altarpiece that is preserved the room of Admiral Christopher Columbus, dedicated to the Virgin of the Navigators. The Renaissance splendor shines also in the halls of Charles V, where are kept magnificent collections of tapestries that narrate the conquest of Tunisia by the Emperor.

In the 19th century rooms were arranged on the upper floor. The old rooms were renovated and embellished with tapestries, furniture, glass lamps of La Granja and a remarkable collection of paintings. In 1931, with the arrival of the Second Republic, the Alcazar was delivered to the city council of Seville. Its interior is formed by rooms beautifully decorated with tiled plasterwork and coffered ceilings wisely combined with splendid courtyards in which the water is indisputable protagonist. All this set creates an atmosphere of an unforgettable beauty and harmony. It emphasizes the Patio of the Maidens, with its wonderful sockets of tiles or the Patio of the Dolls, with its attractive collection of chapiters. The gardens are an authentic vergel, and experienced the same artistic evolution as the Palace: Arabic, Renaissance and Baroque. They occupy 80% of the surface and are arranged in terraces where water is the main element.

The Patio de Banderas was the courtyard of the former Alcázar. This square with orange trees and a simple fountain is flanked by elegant facades and by the Giralda.